We develop a finite-sample, design-based theory for random forests in which each tree is a randomized conditional predictor acting on fixed covariates and the forest is their Monte Carlo average. An exact variance identity separates Monte Carlo error from a covariance floor that persists under infinite aggregation. The floor arises through two mechanisms: observation reuse, where the same training outcomes receive weight across multiple trees, and partition alignment, where independently generated trees discover similar conditional prediction rules. We prove the floor is strictly positive under minimal conditions and show that alignment persists even when sample splitting eliminates observation overlap entirely. We introduce procedure-aligned synthetic resampling (PASR) to estimate the covariance floor, decomposing the total prediction uncertainty of a deployed forest into interpretable components. For continuous outcomes, resulting prediction intervals achieve nominal coverage with a theoretically guaranteed conservative bias direction. For classification forests, the PASR estimator is asymptotically unbiased, providing the first pointwise confidence intervals for predicted conditional probabilities from a deployed forest. Nominal coverage is maintained across a range of design configurations for both outcome types, including high-dimensional settings. The underlying theory extends to any tree-based ensemble with an exchangeable tree-generating mechanism.

Lane-change maneuvers are a leading cause of highway accidents, underscoring the need for accurate intention prediction to improve the safety and decision-making of autonomous driving systems. While prior studies using machine learning and deep learning methods (e.g., SVM, CNN, LSTM, Transformers) have shown promise, most approaches remain limited by binary classification, lack of scenario diversity, and degraded performance under longer prediction horizons. In this study, we propose a physics-informed AI framework that explicitly integrates vehicle kinematics, interaction feasibility, and traffic-safety metrics (e.g., distance headway, time headway, time-to-collision, closing gap time) into the learning process. lane-change prediction is formulated as a three-class problem that distinguishes left change, right change, and no change, and is evaluated across both straight highway segments (highD) and complex ramp scenarios (exiD). By integrating vehicle kinematics with interaction features, our machine learning models, particularly LightGBM, achieve state-of-the-art accuracy and strong generalization. Results show up to 99.8% accuracy and 93.6% macro F1 on highD, and 96.1% accuracy and 88.7% macro F1 on exiD at a 1-second horizon, outperforming a two-layer stacked LSTM baseline. These findings demonstrate the practical advantages of a physics-informed and feature-rich machine learning framework for real-time lane-change intention prediction in autonomous driving systems.

A new pilot program aims to help EMS respond quicker, not act as a replacement. Breakthroughs, discoveries, and DIY tips sent every weekday. When they aren't baffling the public or grounding wildfire planes, drones have some pretty solid uses. Apart from unnecessarily fast same-day deliveries, the pilotless aircrafts may soon become a lifesaving emergency response tool . A collaborative team of health experts, community organizations, and universities are in the middle of a pilot program using drones and automated external defibrillators (AEDs).

Emotion detection from text seeks to identify an individual's emotional or mental state - positive, negative, or neutral - based on linguistic cues. While significant progress has been made for English and other high-resource languages, Bengali remains underexplored despite being the world's fourth most spoken language. The lack of large, standardized datasets classifies Bengali as a low-resource language for emotion detection. Existing studies mainly employ classical machine learning models with traditional feature engineering, yielding limited performance. In this paper, we introduce a new Bengali emotion dataset annotated across eight emotion categories and propose two models for automatic emotion detection: (i) a hybrid Convolutional Recurrent Neural Network (CRNN) model (EmoBangHybrid) and (ii) an AdaBoost-Bidirectional Encoder Representations from Transformers (BERT) ensemble model (EmoBangEnsemble). Additionally, we evaluate six baseline models with five feature engineering techniques and assess zero-shot and few-shot large language models (LLMs) on the dataset. To the best of our knowledge, this is the first comprehensive benchmark for Bengali emotion detection. Experimental results show that EmoBangH and EmoBangE achieve accuracies of 92.86% and 93.69%, respectively, outperforming existing methods and establishing strong baselines for future research.

People Who Say They're Experiencing AI Psychosis Beg the FTC for Help The Federal Trade Commission received 200 complaints mentioning ChatGPT between November 2022 and August 2025. Several attributed delusions, paranoia, and spiritual crises to the chatbot. On March 13, a woman from Salt Lake City, Utah called the Federal Trade Commission to file a complaint against OpenAI's ChatGPT. She claimed to be acting "on behalf of her son, who was experiencing a delusional breakdown." "The consumer's son has been interacting with an AI chatbot called ChatGPT, which is advising him not to take his prescribed medication and telling him that his parents are dangerous," reads the FTC's summary of the call.

Colorectal cancer (CRC) remains the third most prevalent malignancy globally, with approximately 154,000 new cases and 54,000 projected deaths anticipated for 2025. The recent advancement of foundation models in computational pathology has been largely propelled by task agnostic methodologies that can overlook organ-specific crucial morphological patterns that represent distinct biological processes that can fundamentally influence tumor behavior, therapeutic response, and patient outcomes. The aim of this study is to develop a novel, interpretable AI model, PRISM (Prognostic Representation of Integrated Spatial Morphology), that incorporates a continuous variability spectrum within each distinct morphology to characterize phenotypic diversity and reflecting the principle that malignant transformation occurs through incremental evolutionary processes rather than abrupt phenotypic shifts. PRISM is trained on 8.74 million histological images extracted from surgical resection specimens of 424 patients with stage III CRC. PRISM achieved superior prognostic performance for five-year OS (AUC = 0.70 +- 0.04; accuracy = 68.37% +- 4.75%; HR = 3.34, 95% CI = 2.28-4.90; p < 0.0001), outperforming existing CRC-specific methods by 15% and AI foundation models by ~23% accuracy. It showed sex-agnostic robustness (AUC delta = 0.02; accuracy delta = 0.15%) and stable performance across clinicopathological subgroups, with minimal accuracy fluctuation (delta = 1.44%) between 5FU/LV and CPT-11/5FU/LV regimens, replicating the Alliance cohort finding of no survival difference between treatments.

Objective: Electronic health records (EHR) data are prone to missingness and errors. Previously, we devised an "enriched" chart review protocol where a "roadmap" of auxiliary diagnoses (anchors) was used to recover missing values in EHR data (e.g., a diagnosis of impaired glycemic control might imply that a missing hemoglobin A1c value would be considered unhealthy). Still, chart reviews are expensive and time-intensive, which limits the number of patients whose data can be reviewed. Now, we investigate the accuracy and scalability of a roadmap-driven algorithm, based on ICD-10 codes (International Classification of Diseases, 10th revision), to mimic expert chart reviews and recover missing values. Materials and Methods: In addition to the clinicians' original roadmap from our previous work, we consider new versions that were iteratively refined using large language models (LLM) in conjunction with clinical expertise to expand the list of auxiliary diagnoses. Using chart reviews for 100 patients from the EHR at an extensive learning health system, we examine algorithm performance with different roadmaps. Using the larger study of $1000$ patients, we applied the final algorithm, which used a roadmap with clinician-approved additions from the LLM. Results: The algorithm recovered as much, if not more, missing data as the expert chart reviewers, depending on the roadmap. Discussion: Clinically-driven algorithms (enhanced by LLM) can recover missing EHR data with similar accuracy to chart reviews and can feasibly be applied to large samples. Extending them to monitor other dimensions of data quality (e.g., plausability) is a promising future direction.

Community engagement processes in representative political contexts, like school districts, generate massive volumes of feedback that overwhelm traditional synthesis methods, creating barriers to shared understanding not only between civic leaders and constituents but also among community members. To address these barriers, we developed StoryBuilder, a human-AI collaborative pipeline that transforms community input into accessible first-person narratives. Using 2,480 community responses from an ongoing school rezoning process, we generated 124 composite stories and deployed them through a mobile-friendly StorySharer interface. Our mixed-methods evaluation combined a four-month field deployment, user studies with 21 community members, and a controlled experiment examining how narrative composition affects participant reactions. Field results demonstrate that narratives helped community members relate across diverse perspectives. In the experiment, experience-grounded narratives generated greater respect and trust than opinion-heavy narratives. We contribute a human-AI narrative synthesis system and insights on its varied acceptance and effectiveness in a real-world civic context.

This study presents an AI-driven pipeline for automated retinal segmentation and thickness analysis in diabetic retinopathy (DR) using SD-OCT imaging. A deep neural network was trained to segment ten retinal layers, intra-retinal fluid, and hyperreflective foci (HRF), with performance evaluated across multiple architectures. SwinUNETR achieved the highest segmentation accuracy, while VM-Unet excelled in specific layers. Analysis revealed distinct thickness variations between NPDR and PDR, with correlations between layer thickness and visual acuity. The proposed method enhances DR assessment by reducing manual annotation effort and providing clinically relevant thickness maps for disease monitoring and treatment planning.

This work suggests faster and space-efficient index construction algorithms for LSH for Euclidean distance (\textit{a.k.a.}~\ELSH) and cosine similarity (\textit{a.k.a.}~\SRP). The index construction step of these LSHs relies on grouping data points into several bins of hash tables based on their hashcode. To generate an $m$-dimensional hashcode of the $d$-dimensional data point, these LSHs first project the data point onto a $d$-dimensional random Gaussian vector and then discretise the resulting inner product. The time and space complexity of both \ELSH~and \SRP~for computing an $m$-sized hashcode of a $d$-dimensional vector is $O(md)$, which becomes impractical for large values of $m$ and $d$. To overcome this problem, we propose two alternative LSH hashcode generation algorithms both for Euclidean distance and cosine similarity, namely, \CSELSH, \HCSELSH~and \CSSRP, \HCSSRP, respectively. \CSELSH~and \CSSRP~are based on count sketch \cite{count_sketch} and \HCSELSH~and \HCSSRP~utilize higher-order count sketch \cite{shi2019higher}. These proposals significantly reduce the hashcode computation time from $O(md)$ to $O(d)$. Additionally, both \CSELSH~and \CSSRP~reduce the space complexity from $O(md)$ to $O(d)$; ~and \HCSELSH, \HCSSRP~ reduce the space complexity from $O(md)$ to $O(N \sqrt[N]{d})$ respectively, where $N\geq 1$ denotes the size of the input/reshaped tensor. Our proposals are backed by strong mathematical guarantees, and we validate their performance through simulations on various real-world datasets.